hrp0084p1-8 | Adrenal | ESPE2015

Cortisol:Cortisone Ratio and Metalloproteinase 9 Emerging as Risk Factors Associated with Paediatrics Hypertension

Martinez-Aguayo Alejandro , Campino Carmen , Baudrand Rene , Carvajal Cristian , Pinochet Constanza , Garcia Hernan , Bancalari Rodrigo , Tapia Alejandra , Garcia Lorena , Loureiro Carolina , Mendoza Carolina , Vecchiola Andrea , Valdivia Carolina , Fuente Cristobal , Lagos Carlos , Grob Francisca , Solari Sandra , Allende Fidel , Kalergis Alexis , Fardella Carlos

Background: Paediatric hypertension is increasing and has been associated with obesity and insulin resistance. Recently, cortisol:cortisone ratio and the metalloproteinase 9 (MMP9), which is a marker of vascular remodelling, have been syndicated as new risk factors associated with hypertension.Objective and hypotheses: To analyse the association between paediatric hypertension with clinical, biochemical, inflammation, and vascular remodelling biomarkers<...